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KMID : 0366220090440040268
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Korean Journal of Hematology
2009 Volume.44 No. 4 p.268 ~ p.272
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A Case of Solitary Involved NK-T Cell Lymphoma on the Gallbladder
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Ko Hee-Ja
Yang Mi-Yean
Kim Han-Jo
Yun Jin-A
Kim Hyun-Jung
Lee Sang-Cheol
Bae Sang-Byung
Kim Chan-Kyu
Lee Nam-Su
Park Sung-Kyu
Lee Kyu-Taek
Won Jong-Ho
Hong Dae-Sik
Park Hee-Sook
Kim Hee-Kyung
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Abstract
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Extranodal NK-T cell lymphoma is a subtype of non-Hodgkin’s lymphoma (NHL) and this most commonly affects the nasal and paranasal cavities. Primary lymphoma of the gallbladder is extremely rare and solitary relapsed extranodal NK-T cell lymphoma of the gallbladder has not yet been reported in Korea. We experienced a case of a solitary relapsed extranodal NK-T cell lymphoma of the gallbladder. One year earlier, a 55-year-old man was diagnosed with extranodal NK-T cell lymphoma of the anus, and he underwent six cycles of chemotherapy with CHOP (cyclophosphamide, adriamycin, vincristine and prednisone), and he achieved complete remission. The patient was admitted for right upper quadrant pain. Computed tomography (CT) performed on readmission revealed gallbladder wall thickening. Fluorodeoxyglucose-positron emission tomography (FDG-PET) showed hypermetabolic lesions along the gallbladder wall. The specimen obtained at cholecystectomy revealed CD3(+) and CD56(+) lymphoma, which is characteristic of NK-T cell lymphoma. (Korean J Hematol 2009;44:268-272.)
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KEYWORD
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Extranodal NK-T cell lymphoma, Gallbladder cancer, Non-Hodgkin’s lymphoma
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